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KMID : 0363320000210040555
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Journal of Korean Oriental Internal Medicine
2000 Volume.21 No. 4 p.555 ~ p.563
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Experimental Studies of The Effects of Kyungok-go against Mycobacteria tuberculosis
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Jeon Sang-Bok
Jung Doo-Young
Jung Sung-Ki
Rhee Hyung-Koo
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Abstract
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Objective : In order to know the antibacterial effects of Kyungok-go against Mycobacteria tuberculosis,
Methods : In this study, I inverstigated these effects in terms of combination of other antibiotics with and without Kyungok-go on several different media conditions.
Results: On Ogawa medium, Kyungok-go of the 10μ/㎖ concentration showed the anti-Mycobacteria tuberculosis activity against antibiotic drug-sensitive strain. On Middle-blue medium, Kyungok-go of the 10μ/㎖ concentration showed the anti-Mycobacteria tuberculosis activity against antibiotic drug-sensitive strain. Kyungok-go showed the anti mycobacteria tuberculosis activity with the meaningful result above a certain concentration. The resistance against M, tuberculosis as the concentration of Kyungok-go was decreased significantlly on the high concentration(500μ/㎖) When rifampicin and Kyungok-go were used together, the resistance was decreased with the statistical significance as to the persistant antibacterial effect against M. tuberculosis, When ciprofloxacin and Kyungok-go were used together, the resistance was decreased with the statistical significance as to the persistant antibacterial effect against M. tuberculosis, The combination of treatment, Kyungok-go with both rifampicin and ciprofloxacin, showed much better antibacterial effect against M, tuberculosis than antibiotics alone.
Conclusions : This study shows that Kyungok-go has antibacterial effect against M. tuberculosis and in the combination of treatment, Kyungok-go with antibiotics, showed much better antibacterial effect against M. tuberculosis than antibiotics alone,.
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KEYWORD
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Kyungok-go, Mycobacteria tuberculosis
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